Matteo Berrettini has been forced to withdraw from Wimbledon with the tournament losing one its top favourites before he has even played a shot.
Berrettini reach the final at Wimbledon last year and has had another brilliant season on grass in 2022, winning both Stuttgart and Queen's despite just returning from hand surgery.
However, a positive Covid test has left his dreams of adding a Wimbledon crown to that list this year in tatters.
"I am heartbroken to announce that I need to withdraw from Wimbledon due to a positive COVID-19 test result," Matteo Berrettini revealed on social media.
"I have had flu symptoms and been isolating the last few days. Despite symptoms not being severe, I decided it was important to take another test this morning to protect the health and safety of my fellow competitors and everyone else involved in the tournament.
"I have no words to describe the extreme disappointed I feel. The dream is over for this year, but I will be back stronger."
The withdrawal comes on the morning of his first match and just a day after Novak Djokovic talked up his chances of winning the tournament.
"He is definitely top two, three players in the world on grass in the last three years," Djokovic said.
"I mean, his results are testament to that. He has made amazing comeback after a few months' absence from the tour with an injury.
"To win the way he did in Germany and in Queen's is very impressive."
For more exclusive content from Tennisbuzz, including news, features, trivia, promotions and more, please be sure to sign up for our newsletter below or via our home page.
Why not test your tennis knowledge by tackling one of our fiendish quizzes too?